P196: Role of the transcription factor cJun in eosinophil effector function during allergic inflammation
FAU own research funding: EFI / IZKF / EAM ...
Start date : 01.06.2026
End date : 31.05.2027
Project details
Scientific Abstract
Eosinophils are key drivers of allergic airway inflammation. The transcription factor AP-1 (c-Jun) regulates many immune cells, yet its specific role in eosinophils remains unknown. Using eosinophil-specific c-Jun knockout mice, we will analyze how c-Jun controls eosinophil activation, migration, and survival in allergy models, aiming to identify novel therapeutic targets.
Involved:
Contributing FAU Organisations:
Interdisziplinäres Zentrum für Klinische Forschung (IZKF)
Department of Medicine 3 – Rheumatology and Immunology
