D039: EMT specific splicing mediates ferroptosis sensitivity

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.07.2023

End date : 31.12.2025

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Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition (2024) Schwab A, Rao Z, Zhang J, Gollowitzer A, Siebenkäs K, Bindel N, D’Avanzo E, et al. Journal article ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer (2024) Menche C, Schuhwerk H, Armstark I, Gupta P, Fuchs K, van Roey R, Mosa MH, et al. Journal article