IZKF-N8 Lysosomes & glial cells: The role of lysosomal dysfunction within glial cells in Parkinson’s disease

FAU own research funding: EFI / IZKF / EAM ...


Start date : 16.02.2021

End date : 15.02.2023

Extension date: 15.11.2024

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Journal article
Book chapter / Article in edited volumes
Authored book
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Edited Volume
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Unpublished / Preprint

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Abstract

Journal

Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival (2025) Zein L, Dietrich M, Balta D, Bader V, Scheuer C, Zellner S, Weinelt N, et al. Journal article SARS-CoV-2 Spike Protein Induces Time-Dependent CTSL Upregulation in HeLa Cells and Alveolarspheres (2024) Bolsinger M, Drobny A, Wilfling S, Reischl S, Krach F, Moritz R, Balta D, et al. Journal article Late-onset Krabbe disease presenting as spastic paraplegia – implications of GCase and CTSB/D (2024) Mächtel R, Dobert J, Hehr U, Weiß A, Kettwig M, Laugwitz L, Groeschel S, et al. Journal article Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 – Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease (2024) Dobert J, Bub S, Mächtel R, Januliene D, Steger L, Regensburger M, Wilfling S, et al. Journal article Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models (2023) Drobny A, Boros FA, Balta D, Prieto Huarcaya S, Caylioglu D, Qazi N, Vandrey J, et al. Journal article Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models. (2022) Huarcaya AP, Drobny S, Marques ARA, Di Spiezio A, Dobert J, Balta D, Werner C, et al. Journal article, Review article