A089: CD83 as a key regulator during immune homeostasis and neuroinflammation

FAU own research funding: EFI / IZKF / EAM ...


Start date : 01.07.2020

End date : 31.12.2022

Extension date: 30.06.2023

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Abstract

Journal

Microglial expression of CD83 governs cellular activation and restrains neuroinflammation in experimental autoimmune encephalomyelitis (2023) Sinner P, Peckert-Maier K, Mohammadian H, Kuhnt C, Draßner C, Panagiotakopoulou V, Rauber S, et al. Journal article CD83 acts as immediate early response gene in activated macrophages and exhibits specific intracellular trafficking properties (2023) Langguth P, Peckert K, Beck P, Kuhnt C, Draßner C, Deinzer A, Steinkasserer A, Wild A Journal article CD83 expressed by macrophages is an important immune checkpoint molecule for the resolution of inflammation (2023) Peckert-Maier K, Langguth P, Strack A, Stich L, Mühl-Zürbes P, Kuhnt C, Drassner C, et al. Journal article Soluble CD83 improves and accelerates wound healing by the induction of pro-resolving macrophages (2022) Royzman D, Peckert-Maier K, Stich L, König C, Wild A, Tauchi M, Ostalecki C, et al. Journal article The soluble CD83 protein prevents bone destruction by inhibiting the formation of osteoclasts and inducing resolution of inflammation in arthritis (2022) Royzman D, Andreev D, Stich L, Peckert K, Wild A, Zinser E, Mühl-Zürbes P, et al. Journal article The CD83 Molecule – An Important Immune Checkpoint (2020) Grosche L, Knippertz I, König C, Royzman D, Wild A, Zinser E, Sticht H, et al. Journal article, Review article