Biomechanical changes of skeletal muscle in desminopathies - a novel approach to unravel the causes of progressive weakness in inherited muscle diseases

Third party funded individual grant


Start date : 01.07.2014

End date : 30.06.2015

Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice (2017) Diermeier S, Iberl J, Vetter K, Haug M, Pollmann C, Reischl B, Buttgereit A, et al. Journal article The toxic effect of R350P mutant desmin in striated muscle of man and mouse. (2015) Clemen C, Stöckigt F, Strucksberg KH, Chevessier F, Winter L, Schütz J, Bauer R, et al. Journal article, Original article