Design of a recombinant human stem cell line for the development of a novel, animal-free DNT toxicity test

Third party funded individual grant


Start date : 01.04.2013

End date : 31.03.2015

Optimizing neuronal differentiation of human pluripotent NT2 stem cells in monolayer cultures. (2016) Abolpour Mofrad S, Künzel K, Friedrich O, Gilbert D Journal article A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing. (2016) Künzel K, Friedrich O, Gilbert D Journal article, Original article Towards in vitro DT/DNT testing: Assaying chemical susceptibility in early differentiating NT2 cells. (2015) Menzner AK, Abolpour Mofrad S, Friedrich O, Gilbert D Journal article