Ureiro-Cueto G, Nawaz Q, Azari R, Boccaccini AR (2026)
Publication Type: Journal article
Publication year: 2026
Book Volume: 421
Article Number: 140984
DOI: 10.1016/j.matlet.2026.140984
Titanium implants possess excellent mechanical properties; however, their bioinert surfaces limit effective interactions with surrounding bone tissue, potentially compromising long-term stability. Improving the surface characteristics of titanium implants to enhance their biological response remains an important challenge. Here, a novel chitosan (CS)-based composite coating incorporating germanium-containing mesoporous bioactive glass nanoparticles (Ge-MBGNs) was developed and characterized. The resulting coatings exhibited a uniform structure, an average thickness of ∼38 μm and improved adhesion (delamination <5%) indicating suitable mechanical stability and surface wettability compared to CS alone. In vitro tests using MG-63 cells demonstrated that both undoped MBGNs and Ge-MBGNs similarly enhance cell viability compared to pure CS coatings after 24 h. The results indicate that the composite coatings are a viable approach for developing functionalized Ti surfaces.
APA:
Ureiro-Cueto, G., Nawaz, Q., Azari, R., & Boccaccini, A.R. (2026). Synthesis of composite chitosan/Ge-containing mesoporous bioactive glass nanoparticle coatings on titanium surfaces by electrophoretic deposition. Materials Letters, 421. https://doi.org/10.1016/j.matlet.2026.140984
MLA:
Ureiro-Cueto, Guadalupe, et al. "Synthesis of composite chitosan/Ge-containing mesoporous bioactive glass nanoparticle coatings on titanium surfaces by electrophoretic deposition." Materials Letters 421 (2026).
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