Findings from the PM4Onco Workshop on Determining Patient Similarity Search Strategies for Personalized Therapy in Molecular Tumor Boards

Manuilova I, Weise AB, Folwark J, Hiemer S, Schulze S, Benary M, Ustjanzew A, Strantz C, Unberath P, Werle SD, Brors B, Christoph J (2026)

Publication Type: Journal article

Publication year: 2026

Journal

Studies in Health Technology and Informatics IOS Press

Book Volume: 336

Pages Range: 2399-2403

DOI: 10.3233/SHTI260700

Abstract

The PM4Onco project advances precision oncology by developing analytical and visual methods to support data-driven therapy decisions in Molecular Tumor Boards (MTBs). An interdisciplinary workshop at Martin Luther University Halle-Wittenberg in March 2025 explored strategies for defining and integrating patient similarity into MTB workflows. Using a synthetic oncology dataset, participants with clinical and data science backgrounds defined similarity criteria and structured search strategies for patient similarity. The workshop outcomes provide structured decision frameworks that operationalize patient similarity reasoning in a reproducible manner. Their implementation supports transparent and evidence-based analysis, fostering integration between algorithmic modeling and clinical expertise.

Authors with CRIS profile

Cosima Strantz Lehrstuhl für Medizinische Informatik Philipp Unberath Medizinisches Zentrum für Informations- und Kommunikationstechnik (Medizinisches IK-Zentrum, MIK) Jan Christoph

Involved external institutions

Martin-Luther-Universität Halle-Wittenberg (MLU) DE Germany (DE) Universitätsklinikum Halle (Saale) DE Germany (DE) Freie Universität Berlin DE Germany (DE) Universitätsmedizin der Johannes Gutenberg-Universität Mainz DE Germany (DE) Universität Ulm DE Germany (DE) Deutsches Krebsforschungszentrum (DKFZ) DE Germany (DE)

How to cite

APA:

Manuilova, I., Weise, A.B., Folwark, J., Hiemer, S., Schulze, S., Benary, M.,... Christoph, J. (2026). Findings from the PM4Onco Workshop on Determining Patient Similarity Search Strategies for Personalized Therapy in Molecular Tumor Boards. Studies in Health Technology and Informatics, 336, 2399-2403. https://doi.org/10.3233/SHTI260700

MLA:

Manuilova, Iryna, et al. "Findings from the PM4Onco Workshop on Determining Patient Similarity Search Strategies for Personalized Therapy in Molecular Tumor Boards." Studies in Health Technology and Informatics 336 (2026): 2399-2403.

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