Repschläger M, Binder V, Zhao Y, Fahlbusch R, Buchfelder M (2025)
Publication Type: Journal article
Publication year: 2025
Book Volume: 21
Pages Range: 67-73
Journal Issue: 1
DOI: 10.4183/aeb.2025.67
Objective. To assess the outcome of clinical and endocrinological dysfunctions after transsphenoidal decompression in parasellar meningioma. Methods. Retrospective pre-and postoperative evaluation of 40 patients (30 women, 10 men; mean age, 55.9±11.9) who underwent decompressive transsphenoidal microsurgeries. The preoperative investigation took place one month prior surgery, the first follow-up within one week, the second follow-up within three months postoperatively. Results. The most common symptom in our study was diplopia (47.5%, n=19) which showed improvement in 21.1% (n=4) of cases. Preoperative hyperprolactinemia, presented in 52.5% of patients (n=21) with hyperprolactinemia remaining in just 20% of patients (n=8) in the first follow-up. Other endocrine axes were affected less frequently, but also majorly showed improvements. The corticotropic axis was affected in 8.8% (n=3) and remained unchanged. Female gonadotropic axis irritation decreased from 34.5% (n=10) to 31.0% (n=9), male axis deterioration improved in two cases from 50% (n=5) to 30% (n=3). The somatotropic and thyrotropic axes were never negatively affected. Adjuvant radiotherapy was carried out in 60% (n=24) of patients and not yet commenced in an additional nine (22.5%). Conclusion. Experience shows that transsphenoidal decompression is a useful and low complication associated procedure in the initial management of cavernous sinus meningioma.
APA:
Repschläger, M., Binder, V., Zhao, Y., Fahlbusch, R., & Buchfelder, M. (2025). ENDOCRINE DISTURBANCES IN PARASELLAR MENINGIOMAS AND THE EFFECT OF TRANSSPHENOIDAL DECOMPRESSION OPERATIONS. Acta Endocrinologica-Bucharest, 21(1), 67-73. https://doi.org/10.4183/aeb.2025.67
MLA:
Repschläger, Moritz, et al. "ENDOCRINE DISTURBANCES IN PARASELLAR MENINGIOMAS AND THE EFFECT OF TRANSSPHENOIDAL DECOMPRESSION OPERATIONS." Acta Endocrinologica-Bucharest 21.1 (2025): 67-73.
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