Super-resolution label-free Fieldoscopy with attosecond temporal resolution

Jun S, Herbst A, Srivastava A, Deng CZ, Konishi K, Ideguchi T, Scheffter K, Fattahi H (2026)

Publication Type: Conference contribution

Publication year: 2026

Journal

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Publisher: SPIE

Book Volume: 13864

Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Event location: San Francisco, CA, USA

ISBN: 9781510696419

DOI: 10.1117/12.3080403

Abstract

We present a novel technique for broadband, label-free imaging that achieves sub-diffraction spatial resolution and attosecond temporal precision. Using the principle of Femtosecond Fieldoscopy, we generate 2D label-free images by exciting overtone and combination band vibrational modes of a sample in the 1.5 µm – 2.6 µm spectral range. While the conventional optical microscope at this range resolves features down to 2 µm, employing Fieldsocopy allows for the spatial resolution below the diffraction limit of the excitation pulse. Spatial resolution is evaluated using the point spread function (PSF) of 500 nm polystyrene beads and a custom polymer-based resolution target with features from 200 nm to 2 µm. We resolve a PSF below 600 nm (FWHM) for the beads and clearly visualize spatial features on the resolution target down to 650 nm. This is the first demonstration of broadband, label-free super-resolution Fieldoscopy with attosecond temporal resolution.

Authors with CRIS profile

Soyeon Jun
Andreas Herbst
Kilian Scheffter

Involved external institutions

Max-Planck-Institut für die Physik des Lichts (MPL) / Max Planck Institute for the Science of Light DE Germany (DE) National Institute of Materials Science (NIMS) JP Japan (JP) University of Tokyo JP Japan (JP)

How to cite

APA:

Jun, S., Herbst, A., Srivastava, A., Deng, C.Z., Konishi, K., Ideguchi, T.,... Fattahi, H. (2026). Super-resolution label-free Fieldoscopy with attosecond temporal resolution. In Ji-Xin Cheng, Wei Min, Garth J. Simpson (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. San Francisco, CA, USA: SPIE.

MLA:

Jun, Soyeon, et al. "Super-resolution label-free Fieldoscopy with attosecond temporal resolution." Proceedings of the Advanced Chemical Microscopy for Life Science and Translational Medicine 2026, San Francisco, CA, USA Ed. Ji-Xin Cheng, Wei Min, Garth J. Simpson, SPIE, 2026.

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