Effects of Carbon-Based and Organic Nanoparticles in Advanced Dressings for Skin Regeneration: A Review

Rodrigues KF, de Oliveira TC, do Amaral Montanheiro TL, Kito LT, Schatkoski VM, dos Santos AS, Pereira RM, Boccaccini AR, Thim GP, Ünalan I (2025)

Publication Type: Journal article, Review article

Publication year: 2025

Journal

International Wound Journal Wiley

Book Volume: 22

Article Number: e70711

Journal Issue: 7

DOI: 10.1111/iwj.70711

Abstract

Chronic wounds may develop when there is a delay or disturbance in one of the stages of the healing process, presenting challenging financial, clinical, and quality-of-life costs. Therefore, continuous efforts have been made to develop dressings that optimise wound healing. In recent years, nanotechnology has revolutionised wound care, enabling the development of innovative materials with high efficiency that positively impact the healing process. Nanoparticles have been extensively used in wound dressings because of their specific properties, such as a high surface area-to-volume ratio, increased surface reactivity, and improved biocompatibility, representing a unique tissue repair tool. This review article addresses advances in the use of organic nanoparticles in the field of skin regeneration, considering papers published in the last 5 years, and highlighting the effects of this class of materials on the wound healing process. The analysis of the literature shows that the materials being considered are carbon-based and organic materials, including polymeric, cellulosic, lipid, and liposome nanoparticles, which are covered in this review (inorganic nanoparticles are not considered). Furthermore, important aspects to prevent the development of chronic wounds are presented, as well as general characteristics of wounds, the healing process, and their particularities.

Authors with CRIS profile

Aldo Boccaccini Lehrstuhl für Werkstoffwissenschaften (Biomaterialien) Irem Ünalan Lehrstuhl für Werkstoffwissenschaften (Biomaterialien)

Involved external institutions

Instituto Tecnológico de Aeronáutica BR Brazil (BR) Universidade Estadual de Campinas (UNICAMP) / University of Campinas BR Brazil (BR)

How to cite

APA:

Rodrigues, K.F., de Oliveira, T.C., do Amaral Montanheiro, T.L., Kito, L.T., Schatkoski, V.M., dos Santos, A.S.,... Ünalan, I. (2025). Effects of Carbon-Based and Organic Nanoparticles in Advanced Dressings for Skin Regeneration: A Review. International Wound Journal, 22(7). https://doi.org/10.1111/iwj.70711

MLA:

Rodrigues, Karla Faquine, et al. "Effects of Carbon-Based and Organic Nanoparticles in Advanced Dressings for Skin Regeneration: A Review." International Wound Journal 22.7 (2025).

BibTeX: Download