Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome

Beutner D, Bevis N, Loader B, Windisch F, Arndt S, Offergeld C, Wolfram W, Niederwanger L, Zwittag PM, Rubicz N, Schimanski E, Arnoldner C, Riss D, Skarżyński PH, Plichta Ł, Hornung J, Taha L, Lenarz T, Busch S, Magele A, Sprinzl G (2025)


Publication Type: Journal article

Publication year: 2025

Journal

DOI: 10.1097/MAO.0000000000004462

Abstract

Objective Otosclerosis leads to ossification of the stapes footplate and is responsible for a significant number of patients having hearing loss. Stapes surgery is a treatment for otosclerosis with excellent postoperative hearing outcomes. The aim of this retrospective study was to analyze the safety and effectiveness of the titanium mAXIS prosthesis in a multicentric setting. Methods Ninety-four surgeries with implantation of the mAXIS stapes prosthesis took place in a multicenter study group. During follow-up at 59 (±48.1) days, pure-tone audiometry was performed. The pure-tone averages of 0.5, 1, 2, and 3 kHz (PTA-4) were determined. Results No device-related adverse events were reported. There were 88 patients who reported for follow-up, at which pure-tone audiometry was performed. The PTA-4 air-bone gap (ABG) at follow-up was 8.8 (±6.0) dB. In 64.8% of the patients, the postoperative PTA-4 ABG was within 10 dB and in 94.3% it was within 20 dB. The postoperative PTA-4 thresholds for bone conduction were stable in 95.5% of cases. Conclusion The results of this multicentric study demonstrate the safety of the mAXIS titanium stapes prosthesis. The prosthesis shows promising audiological outcomes. Future studies are needed to assess long-term efficacy.

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APA:

Beutner, D., Bevis, N., Loader, B., Windisch, F., Arndt, S., Offergeld, C.,... Sprinzl, G. (2025). Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome. Otology & Neurotology. https://doi.org/10.1097/MAO.0000000000004462

MLA:

Beutner, Dirk, et al. "Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome." Otology & Neurotology (2025).

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