Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome
Beutner D, Bevis N, Loader B, Windisch F, Arndt S, Offergeld C, Wolfram W, Niederwanger L, Zwittag PM, Rubicz N, Schimanski E, Arnoldner C, Riss D, Skarżyński PH, Plichta Ł, Hornung J, Taha L, Lenarz T, Busch S, Magele A, Sprinzl G (2025)
Publication Type: Journal article
Publication year: 2025
Journal
DOI: 10.1097/MAO.0000000000004462
Abstract
Objective Otosclerosis leads to ossification of the stapes footplate and is responsible for a significant number of patients having hearing loss. Stapes surgery is a treatment for otosclerosis with excellent postoperative hearing outcomes. The aim of this retrospective study was to analyze the safety and effectiveness of the titanium mAXIS prosthesis in a multicentric setting. Methods Ninety-four surgeries with implantation of the mAXIS stapes prosthesis took place in a multicenter study group. During follow-up at 59 (±48.1) days, pure-tone audiometry was performed. The pure-tone averages of 0.5, 1, 2, and 3 kHz (PTA-4) were determined. Results No device-related adverse events were reported. There were 88 patients who reported for follow-up, at which pure-tone audiometry was performed. The PTA-4 air-bone gap (ABG) at follow-up was 8.8 (±6.0) dB. In 64.8% of the patients, the postoperative PTA-4 ABG was within 10 dB and in 94.3% it was within 20 dB. The postoperative PTA-4 thresholds for bone conduction were stable in 95.5% of cases. Conclusion The results of this multicentric study demonstrate the safety of the mAXIS titanium stapes prosthesis. The prosthesis shows promising audiological outcomes. Future studies are needed to assess long-term efficacy.
Authors with CRIS profile
Joachim Hornung
Department of Otorhinolaryngology – Head and Neck Surgery (HNO-Klinik)
Lava Taha
Department of Otorhinolaryngology – Head and Neck Surgery (HNO-Klinik)
Involved external institutions
Clinic of the International Center of Hearing and Speech Medincus
Poland (PL)
Medizinische Hochschule Hannover (MHH) / Hannover Medical School
Germany (DE)
Universitätsklinikum St. Pölten
Austria (AT)
Kepler Universitätsklinikum (KUK)
Austria (AT)
Medizinische Universität Wien
Austria (AT)
Klinikum Wels-Grieskirchen
Austria (AT)
Universitätsklinikum Göttingen
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
Poland (PL)
Medizinische Hochschule Hannover (MHH) / Hannover Medical School
Germany (DE)
Universitätsklinikum St. Pölten
Austria (AT)
Kepler Universitätsklinikum (KUK)
Austria (AT)
Medizinische Universität Wien
Austria (AT)
Klinikum Wels-Grieskirchen
Austria (AT)
Universitätsklinikum Göttingen
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
How to cite
APA:
Beutner, D., Bevis, N., Loader, B., Windisch, F., Arndt, S., Offergeld, C.,... Sprinzl, G. (2025). Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome. Otology & Neurotology. https://doi.org/10.1097/MAO.0000000000004462
MLA:
Beutner, Dirk, et al. "Safety and Effectiveness of the Titanium mAXIS Stapes Prosthesis: Multicentric Short-Term Outcome." Otology & Neurotology (2025).
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