Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI

Mokry T, Pantke J, Kauczor HU, Laun FB, Schlemmer HP, Kuder TA, Bickelhaupt S (2025)

Publication Type: Journal article

Publication year: 2025

Journal

Acta Radiologica SAGE Publications

DOI: 10.1177/02841851241313021

Abstract

Background: Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries. Purpose: To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries. Material and Methods: This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3–45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm2 was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm2. Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters Dapp and Kapp were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann–Whitney rank-sum test. Results: Median ADC and Dapp (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371–1.610), 1.619 (range=1.463–1.747), and 1.511 (range=1.423–1.639) at 1.5 T; 1.542 (range=1.428–1.682), 1.658 (range=1.510–1.806), and 1.572 (range=1.455–1.709) at 3 T (P = 0.14, 0.19, and 0.07), whereas median Dapp were 2.024 (range=1.913–2.152), 2.192 (range=2.010–2.327), and 2.045 (range=1.958–2.170) at 1.5 T; 2.013 (range=1.952–2.188), 2.179 (range=2.018–2.327), and 2.082 (range=1.959–2.194) at 3 T (P = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of Kapp revealed significant differences for all timepoints: 0.629 (range=0.595–0.652), 0.604 (range=0.574–0.651), and 0.622 (range=0.581–0.664) at 1.5 T; 0.601 (range=0.563–0.626), 0.567 (range=0.526–0.633), and 0.599 (range=0.541–0.650) at 3 T (P < 0.001, 0.005, and 0.03). Conclusion: Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T.

Authors with CRIS profile

Frederik Bernd Laun Professur für quantitative MR-Bildgebung Sebastian Bickelhaupt Institute of Radiology

Involved external institutions

Universitätsklinikum Heidelberg DE Germany (DE) Medizinische Hochschule Hannover (MHH) / Hannover Medical School DE Germany (DE) Deutsches Krebsforschungszentrum (DKFZ) DE Germany (DE)

How to cite

APA:

Mokry, T., Pantke, J., Kauczor, H.U., Laun, F.B., Schlemmer, H.P., Kuder, T.A., & Bickelhaupt, S. (2025). Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI. Acta Radiologica. https://doi.org/10.1177/02841851241313021

MLA:

Mokry, Theresa, et al. "Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI." Acta Radiologica (2025).

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