European consensus on the histopathology of inflammatory bowel disease

Magro F, Langner C, Driessen A, Ensari A, Geboes K, Mantzaris GJ, Villanacci V, Becheanu G, Nunes PB, Cathomas G, Fries W, Jouret-Mourin A, Mescoli C, de Petris G, Rubio CA, Shepherd NA, Vieth M, Eliakim R (2013)

Publication Type: Journal article

Publication year: 2013

Journal

Book Volume: 7

Pages Range: 827-851

Journal Issue: 10

DOI: 10.1016/j.crohns.2013.06.001

Abstract

The histologic examination of endoscopic biopsies or resection specimens remains a key step in the work-up of affected inflammatory bowel disease (IBD) patients and can be used for diagnosis and differential diagnosis, particularly in the differentiation of UC from CD and other non-IBD related colitides. The introduction of new treatment strategies in inflammatory bowel disease (IBD) interfering with the patients' immune system may result in mucosal healing, making the pathologists aware of the impact of treatment upon diagnostic features. The European Crohn's and Colitis Organisation (ECCO) and the European Society of Pathology (ESP) jointly elaborated a consensus to establish standards for histopathology diagnosis in IBD. The consensus endeavors to address: (i) procedures required for a proper diagnosis, (ii) features which can be used for the analysis of endoscopic biopsies, (iii) features which can be used for the analysis of surgical samples, (iv) criteria for diagnosis and differential diagnosis, and (v) special situations including those inherent to therapy. Questions that were addressed include: how many features should be present for a firm diagnosis? What is the role of histology in patient management, including search for dysplasia? Which features if any, can be used for assessment of disease activity? The statements and general recommendations of this consensus are based on the highest level of evidence available, but significant gaps remain in certain areas. © 2013 European Crohn's and Colitis Organisation.

Involved external institutions

Medizinische Universität Graz Austria (AT) Hospital Network Antwerp / Ziekenhuis Netwerk Antwerpen (ZNA) Belgium (BE) Ankara University / Ankara Üniversitesi Turkey (TR) University Hospital Leuven (UZ) / Universitaire ziekenhuizen Leuven Belgium (BE) Evangelismos Medical Center Greece (GR) Carol Davila University of Medicine and Pharmacy / Universitatea de Medicină și Farmacie „Carol Davila” (UMF București) Romania (RO) University of Lisbon / Universidade de Lisboa (ULisboa) Portugal (PT) University of Messina / Università degli Studi di Messina Italy (IT) Cliniques universitaires Saint-Luc (CHU St-Luc) Belgium (BE) University of Padua / Universita degli Studi di Padova Italy (IT) Mayo Clinic in Arizona United States (USA) (US) Karolinska Institute Sweden (SE) Cheltenham General Hospital United Kingdom (GB) Klinikum Bayreuth Germany (DE) Chaim Sheba Medical Center at Tel HaShomer / המרכז הרפואי עש חיים שיבא – תל השומר‎‎ Israel (IL)

How to cite

APA:

Magro, F., Langner, C., Driessen, A., Ensari, A., Geboes, K., Mantzaris, G.J.,... Eliakim, R. (2013). European consensus on the histopathology of inflammatory bowel disease. Journal of Crohns & Colitis, 7(10), 827-851. https://doi.org/10.1016/j.crohns.2013.06.001

MLA:

Magro, F., et al. "European consensus on the histopathology of inflammatory bowel disease." Journal of Crohns & Colitis 7.10 (2013): 827-851.

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