Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan

Maier H, Hehemann K, Vieth M (2015)


Publication Type: Journal article

Publication year: 2015

Journal

Book Volume: 51

Pages Range: 87-88

Journal Issue: 2

Abstract

An 83-year-old woman with hypertension received the angiotensin-II receptor type 1 blocker (ARB) eprosartan for more than 10 years. Six months ago, the dosage of the drug was doubled, and the patient reported a sudden onset of diarrhea. Duodenal biopsies showed a celiac disease-like pathology with flattened mucosa and an increase of intraepithelial lymphocytes and eosinophils, but serology of celiac disease remained negative. Celiac disease-like changes have been previously reported to be associated with other ARBs. This is the first case following eprosartan medication. In celiac-disease-like pathology of the small bowel with negative serology, drug-induced changes, for example due to ARBs, should be excluded.

How to cite

APA:

Maier, H., Hehemann, K., & Vieth, M. (2015). Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan. Cesko-Slovenska Patologie a Soudni Lekarstvi, 51(2), 87-88.

MLA:

Maier, Hans, Karlheinz Hehemann, and Michael Vieth. "Celiac disease-like enteropathy due to antihypertensive therapy with the angiotensin-II receptor type 1 inhibitor eprosartan." Cesko-Slovenska Patologie a Soudni Lekarstvi 51.2 (2015): 87-88.

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