Magnetomotive Displacement of Magnetic Nanoparticles in Different Tissue Phantoms

Huber C, Heim C, Li J, Ermert H, Rupitsch SJ, Ullmann I, Lyer S (2024)

Publication Type: Journal article

Publication year: 2024

Journal

Book Volume: 10

Pages Range: 324-327

Issue: 4

DOI: 10.1515/cdbme-2024-2079

Abstract

Magnetic  nanoparticles  (MNPs)  can  be  used  invarious  biomedical  applications,  such  as  magnetic  drug  tar-geting (MDT) or magnetic hyperthermia for cancer treatment.MNPs  are  injected  into  the  body  and  accumulated  with  anexternal  magnetic  field  at  the  tumor  site.  For  therapy  mon-itoring,  the  MNPs  distribution  has  to  be  accurately  mappedin  real  time.  Magnetomotive  ultrasound  (MMUS)  is  a  suit-able technique for this purpose. It was already demonstratedthat MMUS can map the accumulation process of MNPs dur-ing MDT. Moreover, inverse MMUS is an advanced techniqueto quantify MNP distribution. This method simulates the dis-placement of MNPs and surrounding tissues and compares theresults to measured data. Understanding how magnetomotivedisplacement behaves in various elastic environments is cru-cial for advancing inverse MMUS and accurately quantifyingMNP distributions. In this study, ultrasound tissue phantomswere fabricated with varying elastic parameters, incorporatingMNPs. Subsequently, their MMUS displacement is assessed.

Authors with CRIS profile

Involved external institutions

Albert-Ludwigs-Universität Freiburg Germany (DE)

How to cite

APA:

Huber, C., Heim, C., Li, J., Ermert, H., Rupitsch, S.J., Ullmann, I., & Lyer, S. (2024). Magnetomotive Displacement of Magnetic Nanoparticles in Different Tissue Phantoms. Current Directions in Biomedical Engineering, 10, 324-327. https://doi.org/10.1515/cdbme-2024-2079

MLA:

Huber, Christian, et al. "Magnetomotive Displacement of Magnetic Nanoparticles in Different Tissue Phantoms." Current Directions in Biomedical Engineering 10 (2024): 324-327.

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