Eosinophils as modulators of host defense during parasitic, fungal, bacterial, and viral infections
Gazzinelli-Guimaraes PH, Jones SM, Vöhringer D, Mayer-Barber KD, Samarasinghe AE (2024)
Publication Type: Journal article, Review article
Publication year: 2024
Journal
Book Volume: 116
Pages Range: 1301-1323
Journal Issue: 6
Abstract
Eosinophils, traditionally associated as central innate effector cells with type 2 immunity during allergic and helminth parasitic diseases, have recently been revealed to have important roles in tissue homeostasis as well as host defense in a broader variety of infectious diseases. In a dedicated session at the 2023 biennial conference of the International Eosinophil Society titled “Eosinophils in Host Defense,” the multifaceted roles eosinophils play against diverse pathogens, ranging from parasites to fungi, bacteria, and viruses, were presented. In this review, the session speakers offer a comprehensive summary of recent discoveries across pathogen classes, positioning eosinophils as pivotal leukocytes in both host defense and pathology. By unraveling the intricacies of eosinophil engagement in host resistance, this exploration may provide valuable insights not only to understand specific underpinnings of eosinophil functions related to each class of pathogens but also to develop novel therapeutics effective against a broad spectrum of infectious diseases.
Authors with CRIS profile
Involved external institutions
George Washington University (GWU)
United States (USA) (US)
National Institute of Allergy and Infectious Diseases
United States (USA) (US)
The University of Tennessee Health Science Center
United States (USA) (US)
United States (USA) (US)
National Institute of Allergy and Infectious Diseases
United States (USA) (US)
The University of Tennessee Health Science Center
United States (USA) (US)
How to cite
APA:
Gazzinelli-Guimaraes, P.H., Jones, S.M., Vöhringer, D., Mayer-Barber, K.D., & Samarasinghe, A.E. (2024). Eosinophils as modulators of host defense during parasitic, fungal, bacterial, and viral infections. Journal of Leukocyte Biology, 116(6), 1301-1323. https://doi.org/10.1093/jleuko/qiae173
MLA:
Gazzinelli-Guimaraes, Pedro H., et al. "Eosinophils as modulators of host defense during parasitic, fungal, bacterial, and viral infections." Journal of Leukocyte Biology 116.6 (2024): 1301-1323.
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