Risk factors associated with complications of palliative drainage of ascites with tunneled peritoneal catheters

Machnik D, Fischer S, Vetter M, Lamprecht-Bailer R, Rouse-Merkel R, Klett D, Neurath M, Strobel D, Zundler S, Haberkamp S (2025)

Publication Type: Journal article

Publication year: 2025

Journal

Therapeutic Advances in Gastroenterology SAGE Publications

Book Volume: 18

DOI: 10.1177/17562848241310183

Abstract

Background: Medically intractable ascites causes substantial distress in patients with palliative disease. Tunneled peritoneal catheters have been established as a feasible treatment option allowing patient-controlled paracentesis in a homecare setting. However, while a range of complications is associated with these drainages, risk factors for complications have not been identified so far. Objectives: To explore potential risk factors associated with complications of tunneled peritoneal catheters. Design: Retrospective observational cohort study. Methods: Single-center cohort comprising 49 patients with palliative disease receiving 57 tunneled peritoneal catheters at a tertiary care hospital. Results: Catheter placement was successful in all patients and associated with low numbers of severe complications. Our data suggest a higher risk for severe late complications in patients with benign disease, with drainage replacement, and when performed by less experienced physicians. Conclusion: Tunneled peritoneal catheters are an effective and safe option to treat symptomatic ascites in patients with end-stage palliative disease. The indication should be carefully considered in patients with benign disease and after removal or dislocation of a previous catheter.

Authors with CRIS profile

Sarah Fischer Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Marcel Vetter Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Ricarda Lamprecht-Bailer Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Daniel Klett Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Markus Neurath Lehrstuhl für Innere Medizin I (Medizin 1) Deike Strobel Medizinische Fakultät Sebastian Zundler Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology Sophie Haberkamp Department of Medicine 1 – Gastroenterology, Pneumology and Endocrinology

How to cite

APA:

Machnik, D., Fischer, S., Vetter, M., Lamprecht-Bailer, R., Rouse-Merkel, R., Klett, D.,... Haberkamp, S. (2025). Risk factors associated with complications of palliative drainage of ascites with tunneled peritoneal catheters. Therapeutic Advances in Gastroenterology, 18. https://doi.org/10.1177/17562848241310183

MLA:

Machnik, Domenique, et al. "Risk factors associated with complications of palliative drainage of ascites with tunneled peritoneal catheters." Therapeutic Advances in Gastroenterology 18 (2025).

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