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Accuracy of Coronary Plaque Detection and Assessment of Interobserver Agreement for Plaque Quantification Using Automatic Coronary Plaque Analysis Software on Coronary CT Angiography Genauigkeit der Koronarplaque-Detektion und Beurteilung der Interobserver-Übereinstimmung von Plaquequantifizierung unter Verwendung einer automatischen Koronarplaqueanalyse-Software in der Koronar-CT-Angiografie

Laqmani A, Klink T, Quitzke M, Creder DD, Adam G, Lund G (2016)

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Publication Type: Journal article

Publication year: 2016

Journal

Book Volume: 188

Pages Range: 933-939

Journal Issue: 10

DOI: 10.1055/s-0042-110099

Abstract

Purpose: To evaluate the accuracy of automatic plaque detection and the interobserver agreement of automatic versus manually adjusted quantification of coronary plaques on coronary CT angiography (cCTA) using commercially available software. Materials and Methods: 10 cCTA datasets were evaluated using plaque software. First, the automatically detected plaques were verified. Second, two observers independently performed plaque quantification without revising the automatically constructed plaque contours (automatic approach). Then, each observer adjusted the plaque contours according to plaque delineation (adjusted approach). The interobserver agreement of both approaches was analyzed. Results: 32 of 114 automatically identified findings were true-positive plaques, while 82 (72 %) were false-positive. 20 of 52 plaques (38 %) were missed by the software (false-negative). The automatic approach provided good interobserver agreement with relative differences of 0.9 ± 16.0 % for plaque area and -3.3 ± 33.8 % for plaque volume. Both observers independently adjusted all contours because they did not represent the plaque delineation. Interobserver agreement decreased for the adjusted approach with relative differences of 25.0 ± 24.8 % for plaque area and 20.0 ± 40.4 % for plaque volume. Conclusion: The automatic plaque analysis software is of limited value due to high numbers of false-positive and false-negative plaque findings. The automatic approach was reproducible but it necessitated adjustment of all constructed plaque contours resulting in deterioration of the interobserver agreement.

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How to cite

APA:

Laqmani, A., Klink, T., Quitzke, M., Creder, D.D., Adam, G., & Lund, G. (2016). Accuracy of Coronary Plaque Detection and Assessment of Interobserver Agreement for Plaque Quantification Using Automatic Coronary Plaque Analysis Software on Coronary CT Angiography Genauigkeit der Koronarplaque-Detektion und Beurteilung der Interobserver-Übereinstimmung von Plaquequantifizierung unter Verwendung einer automatischen Koronarplaqueanalyse-Software in der Koronar-CT-Angiografie. Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 188(10), 933-939. https://doi.org/10.1055/s-0042-110099

MLA:

Laqmani, A., et al. "Accuracy of Coronary Plaque Detection and Assessment of Interobserver Agreement for Plaque Quantification Using Automatic Coronary Plaque Analysis Software on Coronary CT Angiography Genauigkeit der Koronarplaque-Detektion und Beurteilung der Interobserver-Übereinstimmung von Plaquequantifizierung unter Verwendung einer automatischen Koronarplaqueanalyse-Software in der Koronar-CT-Angiografie." Röfo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 188.10 (2016): 933-939.

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