Civelek M, Cicha I, Spielvogel H, Tietze R, Lyer S, Janko C, Alexiou C (2024)
Publication Language: English
Publication Type: Journal article
Publication year: 2024
Book Volume: 19
Pages Range: 1711-1716
Journal Issue: 21-22
DOI: 10.1080/17435889.2024.2380242
Phytochemicals are natural bioactive compounds produced by plants. Their role is to protect the host from pathogens or predators and, as the components of herbal remedies, they have been used since antiquity in traditional medicine, showing e.g. anti-inflammatory, antibacterial, antiviral, or lipid-lowering properties. Despite the growing interest in this class of drugs, a large gap exists between the expected activity of the phytochemicals and their effective use in therapies, mainly due to their poor bioavailability upon oral administration and individual differences in metabolism. Encapsulating these potent substances in nanocarriers that enable extended circulation time, or provide enteric coating to protect the orally administered phytochemicals, is expected to increase the bioavailability of the drugs and potentially allow their controlled release. This article highlights some recent reports addressing the development of nanocarriers for phytochemicals with therapeutic potential in human diseases.
APA:
Civelek, M., Cicha, I., Spielvogel, H., Tietze, R., Lyer, S., Janko, C., & Alexiou, C. (2024). Nanocarriers for therapeutic phytochemicals. Nanomedicine, 19(21-22), 1711-1716. https://doi.org/10.1080/17435889.2024.2380242
MLA:
Civelek, Mehtap, et al. "Nanocarriers for therapeutic phytochemicals." Nanomedicine 19.21-22 (2024): 1711-1716.
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