Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges
Möckl L, Moerner WE (2020)
Publication Type: Journal article, Review article
Publication year: 2020
Journal
Book Volume: 142
Pages Range: 17828-17844
Journal Issue: 42
DOI: 10.1021/jacs.0c08178
Abstract
Single-molecule super-resolution microscopy has developed from a specialized technique into one of the most versatile and powerful imaging methods of the nanoscale over the past two decades. In this perspective, we provide a brief overview of the historical development of the field, the fundamental concepts, the methodology required to obtain maximum quantitative information, and the current state of the art. Then, we will discuss emerging perspectives and areas where innovation and further improvement are needed. Despite the tremendous progress, the full potential of single-molecule super-resolution microscopy is yet to be realized, which will be enabled by the research ahead of us.
Involved external institutions
United States (USA) (US)How to cite
APA:
Möckl, L., & Moerner, W.E. (2020). Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges. Journal of the American Chemical Society, 142(42), 17828-17844. https://doi.org/10.1021/jacs.0c08178
MLA:
Möckl, Leonhard, and W. E. Moerner. "Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges." Journal of the American Chemical Society 142.42 (2020): 17828-17844.
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