Closed Loop Molecular Communication Testbed: Setup, Interference Analysis, and Experimental Results

Brand L, Scherer M, tom Dieck T, Lotter S, Schäfer M, Burkovski A, Sticht H, Castiglione K, Schober R (2024)

Publication Language: English

Publication Type: Conference contribution

Publication year: 2024

Publisher: Institute of Electrical and Electronics Engineers, Inc.

Pages Range: 4805-4811

Conference Proceedings Title: ICC 2024 - IEEE International Conference on Communications

Event location: Denver, CO US

ISBN: 978-1-7281-9054-9

DOI: 10.1109/ICC51166.2024.10622231

Abstract

In this paper, we present a fluid-based experimental molecular communication (M C) testbed that, similar to the human cardiovascular system, operates in a closed circuit tube system. The proposed system is designed to be biocompatible, resource-efficient, and controllable from outside the tube. As signaling molecule, the testbed employs the green fluorescent protein variant “Dreiklang” (GFPD). GFPDs can be reversibly switched via light of different wavelengths between a bright fluorescent state and a less fluorescent state. Hence, this property allows for writing and erasing information encoded in the state of the G FPDs already present in the fluid via radiation from outside the tube. The concept of modulating the GFPDs existing in the channel at the transmitter for information transmission, instead of releasing new molecules, is a form of media modulation. In our testbed, due to the closed loop setup and the long experiment durations of up to 250 min, we observe new forms of inter-symbol interferences (ISI), which do not occur in short experiments and open loop systems. In particular, up to four different forms of ISI, namely channel ISI, inter-loop ISI, offset ISI, and permanent ISI, occur in the considered system. To mitigate inter-loop ISI and offset ISI, we propose a light based eraser unit. We experimentally demonstrate reliable information transmission in our testbed achieving error-free transmission of 500 bit at a data rate of 6 bit min −1 based on a sub-optimal low-complexity detection scheme.

Authors with CRIS profile

Lukas Brand Lehrstuhl für Digitale Übertragung Maike Scherer Lehrstuhl für Bioverfahrenstechnik Teena tom Dieck Lehrstuhl für Digitale Übertragung Sebastian Lotter Graduiertenkolleg 2950 Synthetische molekulare Kommunikation über unterschiedliche Größenordnungen: Von der Theorie bis zu Experimenten Maximilian Schäfer Lehrstuhl für Digitale Übertragung Andreas Burkovski Professur für Mikrobiologie Heinrich Sticht Professur für Bioinformatik Kathrin Castiglione Lehrstuhl für Bioverfahrenstechnik Robert Schober Lehrstuhl für Digitale Übertragung

Additional Organisation(s)

FAU Forschungszentrum Neue Wirkstoffe (FAU NeW)

How to cite

APA:

Brand, L., Scherer, M., tom Dieck, T., Lotter, S., Schäfer, M., Burkovski, A.,... Schober, R. (2024). Closed Loop Molecular Communication Testbed: Setup, Interference Analysis, and Experimental Results. In ICC 2024 - IEEE International Conference on Communications (pp. 4805-4811). Denver, CO, US: Institute of Electrical and Electronics Engineers, Inc..

MLA:

Brand, Lukas, et al. "Closed Loop Molecular Communication Testbed: Setup, Interference Analysis, and Experimental Results." Proceedings of the ICC 2024 - IEEE International Conference on Communications, Denver, CO Institute of Electrical and Electronics Engineers, Inc., 2024. 4805-4811.

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