Electromagnetic Field-Induced Electrotaxis as a Mechanism for Reducing the Neuroanatomical Gap in Cochlear Implants
Delipetar B, Borić T, Žarković J, Radotić V, Bedalov A, Kovačić D (2024)
Publication Type: Conference contribution
Publication year: 2024
Publisher: Institute of Electrical and Electronics Engineers Inc.
Conference Proceedings Title: 2024 9th International Conference on Smart and Sustainable Technologies, SpliTech 2024
Event location: Bol and Split, HRV
ISBN: 9789532901351
DOI: 10.23919/SpliTech61897.2024.10612394
Abstract
Spiral ganglion neurons (SGNs) are the primary auditory neurons in the cochlea that play a key role in connecting the auditory input and the cochlear nucleus. Damage to auditory hair cells without the possibility of regeneration causes irreversible hearing loss. A cochlear implant (CI) is an advanced and effective prosthetic device that converts sound from the environment into an electrical signal that is sent via electrodes directly to the SGNs and thus bypasses damaged auditory hair cells. However, a significant part of users still cannot achieve a satisfactory improvement in hearing quality. One of the causes of this is the neuroanatomical gap (NAG) between electrodes and cells, due to which, in some cases, it is not possible to achieve sufficient contact between electrodes and neurons. This paper explores the mechanism of global electromagnetic field (EMF)-induced electrotaxis as one potential way to reduce NAG. In the experiment, SGNs from P5-P7 rats were cultivated on microchips with customized microtopography and glass coverslips surrounded by a magnetic coil. The effect on the morphological properties of neurons was analyzed from the perspective of further research.
Involved external institutions
Max-Planck-Zentrum für Physik und Medizin (MPZPM)
Germany (DE)
University of Split / Sveučilište u Splitu
Croatia (HR)
Germany (DE)
University of Split / Sveučilište u Splitu
Croatia (HR)
How to cite
APA:
Delipetar, B., Borić, T., Žarković, J., Radotić, V., Bedalov, A., & Kovačić, D. (2024). Electromagnetic Field-Induced Electrotaxis as a Mechanism for Reducing the Neuroanatomical Gap in Cochlear Implants. In Petar Solic, Sandro Nizetic, Joel J. P. C. Rodrigues, Joel J.P.C. Rodrigues, Diego Lopez-de-Ipina Gonzalez-de-Artaza, Toni Perkovic, Luca Catarinucci, Luigi Patrono (Eds.), 2024 9th International Conference on Smart and Sustainable Technologies, SpliTech 2024. Bol and Split, HRV: Institute of Electrical and Electronics Engineers Inc..
MLA:
Delipetar, Boris, et al. "Electromagnetic Field-Induced Electrotaxis as a Mechanism for Reducing the Neuroanatomical Gap in Cochlear Implants." Proceedings of the 9th International Conference on Smart and Sustainable Technologies, SpliTech 2024, Bol and Split, HRV Ed. Petar Solic, Sandro Nizetic, Joel J. P. C. Rodrigues, Joel J.P.C. Rodrigues, Diego Lopez-de-Ipina Gonzalez-de-Artaza, Toni Perkovic, Luca Catarinucci, Luigi Patrono, Institute of Electrical and Electronics Engineers Inc., 2024.
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