Düll M, Kremer A (2024)
Publication Type: Journal article
Publication year: 2024
DOI: 10.1007/s00105-024-05380-1
Background: Chronic pruritus affecting primary non-lesional skin (CPNL) manifests as a common symptom across a spectrum of diseases spanning various medical specialties. Given the diverse etiological factors involved, diagnosing the underlying condition poses a significant challenge. Objectives: To provide a comprehensive overview of clinical, laboratory, and imaging diagnostics for CPNL. Materials and methods: A thorough literature search on the diagnostics of chronic pruritus was conducted using PubMed with specific keywords “chronic pruritus AND non-lesional skin”, “chronic itch AND non-lesional skin”, “chronic pruritus AND diagnostics”, “chronic itch AND diagnostics”, “CKD-aP”, “hepatic pruritus”, “cholestatic pruritus”, and “myeloproliferative neoplasms AND pruritus”. Results: A systematic diagnostic approach is recommended for patients with CPNL, guided by the prevalence of pruritus-associated diseases. Initial basic diagnostics facilitate a cost-effective and focused evaluation during the initial medical assessment. Information pertaining to underlying diseases can be further refined through specialized diagnostic procedures. Conclusions: CPNL often presents a diagnostic dilemma. Adopting a stepwise diagnostic strategy facilitates the identification of underlying etiologies, which is crucial for recognizing diseases and administering pruritus-specific pharmacotherapy.
APA:
Düll, M., & Kremer, A. (2024). Recommended diagnostics for pruritus affecting primary non-lesional skin Empfohlene Diagnostik bei Pruritus auf primär unveränderter Haut. Die Dermatologie. https://doi.org/10.1007/s00105-024-05380-1
MLA:
Düll, Miriam, and Andreas Kremer. "Recommended diagnostics for pruritus affecting primary non-lesional skin Empfohlene Diagnostik bei Pruritus auf primär unveränderter Haut." Die Dermatologie (2024).
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