Real-world treatment of metastatic hormone-sensitive prostate cancer in the USA, Europe and Asia

Goebell P, Raina R, Chen S, Rege S, Shah R, Grossman JP, Waldeck AR (2024)


Publication Type: Journal article

Publication year: 2024

Journal

Book Volume: 20

Pages Range: 903-918

Journal Issue: 14

DOI: 10.2217/fon-2023-0814

Abstract

Aim: To characterize real-world patients with metastatic hormone-sensitive prostate cancer (mHSPC) and treating physicians and evaluate treatment trends and baseline concordance versus guidelines internationally. Materials & methods: Retrospective, cross-sectional data from the Ipsos Global Oncology Monitor database 2018-2020 were used for descriptive analysis of mHSPC patients, treating physicians and treatment utilization. Results: Among the 6198 mHSPC patients from five countries, the most common treatment was either androgen deprivation therapy (ADT) monotherapy or first-generation androgen receptor inhibitor + ADT. Second-generation androgen receptor inhibitor use was only initiating but increasing over the study period. Conclusion: Despite contemporaneous guidelines recommending treatment intensification of ADT in combination with novel antihormonals or docetaxel, 76.1% of reported mHSPC patients received non-guideline-concordant care.

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How to cite

APA:

Goebell, P., Raina, R., Chen, S., Rege, S., Shah, R., Grossman, J.P., & Waldeck, A.R. (2024). Real-world treatment of metastatic hormone-sensitive prostate cancer in the USA, Europe and Asia. Future Oncology, 20(14), 903-918. https://doi.org/10.2217/fon-2023-0814

MLA:

Goebell, Peter, et al. "Real-world treatment of metastatic hormone-sensitive prostate cancer in the USA, Europe and Asia." Future Oncology 20.14 (2024): 903-918.

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