(2006)
Publication Type: Journal article
Publication year: 2006
Book Volume: 13
Pages Range: 806-809
Journal Issue: 7
DOI: 10.1128/CVI.00092-06
In mice, Anaplasma phagocytophilum control is independent of phagocyte oxidase (phox), inducible NO synthase (NOS2), tumor necrosis factor (TNF), and MyD88 Toll-like receptor signaling. We show that despite evasion of these host responses, phox, NOS2, TNF, and MyD88 are activated and contribute to inflammation and hepatic injury more than A. phagocytophilum itself. Copyright © 2006, American Society for Microbiology. All Rights Reserved.