α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength

Thomas WA, Boscher C, Chu YS, Cuvelier D, Martinez-Rico C, Seddiki R, Heysch J, Ladoux B, Thiery JP, Mege RM, Dufour S (2013)


Publication Type: Journal article

Publication year: 2013

Journal

Book Volume: 288

Pages Range: 4957-4969

Journal Issue: 7

DOI: 10.1074/jbc.M112.403774

Abstract

Background: Cadherin interactions with catenins are crucial for intercellular adhesion. Results: αE-catenin and vinculin cooperate to promote the time-dependent reinforcement of cadherin-mediated adhesions. Conclusion: aE-catenin and vinculin form a mechanoresponsive link between cadherin and the underlying actin cytoskeleton. Significance: The force-dependent modulation of a-catenin and vinculin recruitment contributes to the development of cadherin adhesion strength.© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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APA:

Thomas, W.A., Boscher, C., Chu, Y.S., Cuvelier, D., Martinez-Rico, C., Seddiki, R.,... Dufour, S. (2013). α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength. Journal of Biological Chemistry, 288(7), 4957-4969. https://doi.org/10.1074/jbc.M112.403774

MLA:

Thomas, William A., et al. "α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength." Journal of Biological Chemistry 288.7 (2013): 4957-4969.

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