Kalman Inversion Stress Microscopy

Nier V, Peyret G, d'Alessandro J, Ishihara S, Ladoux B, Marcq P (2018)

Publication Type: Journal article

Publication year: 2018

Journal

Biophysical Journal Biophysical Society

Book Volume: 115

Pages Range: 1808-1816

Journal Issue: 9

DOI: 10.1016/j.bpj.2018.09.013

Abstract

Although mechanical cues are crucial to tissue morphogenesis and development, the tissue mechanical stress field remains poorly characterized. Given traction force time-lapse movies, as obtained by traction force microscopy of in vitro cellular sheets, we show that the tissue stress field can be estimated by Kalman filtering. After validation using numerical data, we apply Kalman inversion stress microscopy to experimental data. We combine the inferred stress field with velocity and cell-shape measurements to quantify the rheology of epithelial cell monolayers in physiological conditions, found to be close to that of an elastic and active material.

Authors with CRIS profile

Benoit Ladoux

Involved external institutions

Institut Curie FR France (FR) Institut Jacques Monod (IJM) FR France (FR) University of Tokyo JP Japan (JP)

How to cite

APA:

Nier, V., Peyret, G., d'Alessandro, J., Ishihara, S., Ladoux, B., & Marcq, P. (2018). Kalman Inversion Stress Microscopy. Biophysical Journal, 115(9), 1808-1816. https://doi.org/10.1016/j.bpj.2018.09.013

MLA:

Nier, Vincent, et al. "Kalman Inversion Stress Microscopy." Biophysical Journal 115.9 (2018): 1808-1816.

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