Increased blood pressure after nonsevere COVID-19
Schmidt-Lauber C, Alba Schmidt E, Hänzelmann S, Petersen EL, Behrendt CA, Twerenbold R, Blankenberg S, Huber TB, Wenzel UO (2023)
Publication Type: Journal article
Publication year: 2023
Journal
Book Volume: 41
Pages Range: 1721-1729
Journal Issue: 11
DOI: 10.1097/HJH.0000000000003522
Abstract
BACKGROUND: Various sequelae have been described after nonsevere coronavirus disease 2019 (COVID-19), but knowledge on postacute effects on blood pressure is limited. METHODS: This is a cross-sectional analysis of blood pressure profiles in individuals after nonsevere COVID-19 compared with matched population-based individuals without prior COVID-19. Data were derived from the ongoing and prospective Hamburg City Health Study, a population-based study in Hamburg, Germany, and its associated COVID-19 program, which included individuals at least 4 months after COVID-19. Matching was performed by age, sex, education, and preexisting hypertension in a 1 : 4 ratio. RESULTS: Four hundred and thirty-two individuals after COVID-19 (mean age 56.1 years) were matched to 1728 controls without prior COVID-19 (56.2 years). About 92.8% of COVID-19 courses were mild or moderate, only 7.2% were hospitalized, and no individual had been treated on an intensive care unit. Even after adjustment for relevant competing risk factors, DBP [+4.7 mmHg, 95% confidence interval (95% CI) 3.97-5.7, P < 0.001] was significantly higher in individuals after COVID-19. For SBP, a trend towards increased values was observed (+1.4 mmHg, 95% CI -0.4 to 3.2, P = 0.120). Hypertensive blood pressures at least 130/80 mmHg (according to the ACC/AHA guideline) and at least 140/90 mmHg (ESC/ESH guideline) occurred significantly more often in individuals after COVID-19 than matched controls (odds ratio 2.0, 95% CI 1.5-2.7, P < 0.001 and odds ratio 1.6, 95% CI 1.3-2.0, P < 0.001, respectively), mainly driven by changes in DBP. CONCLUSION: Blood pressure is higher in individuals after nonsevere COVID-19 compared with uninfected individuals suggesting a significant hypertensive sequela.
Involved external institutions
Germany (DE)How to cite
APA:
Schmidt-Lauber, C., Alba Schmidt, E., Hänzelmann, S., Petersen, E.L., Behrendt, C.A., Twerenbold, R.,... Wenzel, U.O. (2023). Increased blood pressure after nonsevere COVID-19. Journal of Hypertension, 41(11), 1721-1729. https://doi.org/10.1097/HJH.0000000000003522
MLA:
Schmidt-Lauber, Christian, et al. "Increased blood pressure after nonsevere COVID-19." Journal of Hypertension 41.11 (2023): 1721-1729.
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