Grieshaber-Bouyer R, Nigrovic PA (2019)
Publication Type: Journal article, Review article
Publication year: 2019
Book Volume: 10
Article Number: 346
Journal Issue: MAR
Neutrophils are versatile innate effector cells essential for immune defense but also responsible for pathologic inflammation. This dual role complicates therapeutic targeting. However, neither neutrophils themselves nor the mechanisms they employ in different forms of immune responses are homogeneous, offering possibilities for selective intervention. Here we review heterogeneity within the neutrophil population as well as in the pathways mediating neutrophil recruitment to inflamed tissues with a view to outlining opportunities for therapeutic manipulation in inflammatory disease.
APA:
Grieshaber-Bouyer, R., & Nigrovic, P.A. (2019). Neutrophil heterogeneity as therapeutic opportunity in immune-mediated disease. Frontiers in Immunology, 10(MAR). https://doi.org/10.3389/fimmu.2019.00346
MLA:
Grieshaber-Bouyer, Ricardo, and Peter A. Nigrovic. "Neutrophil heterogeneity as therapeutic opportunity in immune-mediated disease." Frontiers in Immunology 10.MAR (2019).
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