Mutlu MY, Tascilar K, Schett G (2023)
Publication Type: Journal article, Review article
Publication year: 2023
DOI: 10.1016/j.rhum.2023.07.019
The advent of biologic disease modifying anti-rheumatic drugs (bDMARDs) has considerably improved patient outcomes in inflammatory arthritis. However, not all patients reach the state of remission as disease can be resistant even to single cytokine inhibition by bDMARDs. Simultaneous or sequential inhibition of multiple cytokines may be considered in situations, where disease control is not adequate under singular inhibition of cytokines. Although there have been some disappointing experiences in the past with combination of bDMARDs, the ongoing improvement of our understanding about inflammatory pathways and the overall better safety understanding of bDMARDs seem to make new biologic treatment combinations possible. This review covers the rationale and current evidence for bDMARDs combination in inflammatory arthritis.
APA:
Mutlu, M.Y., Tascilar, K., & Schett, G. (2023). Rationnel, état des lieux et perspectives des combinaisons de traitements de fond biologiques dans la prise en charge de la polyarthrite rhumatoïde et du rhumatisme psoriasique. Revue du Rhumatisme (Edition Francaise). https://doi.org/10.1016/j.rhum.2023.07.019
MLA:
Mutlu, Melek Yalcin, Koray Tascilar, and Georg Schett. "Rationnel, état des lieux et perspectives des combinaisons de traitements de fond biologiques dans la prise en charge de la polyarthrite rhumatoïde et du rhumatisme psoriasique." Revue du Rhumatisme (Edition Francaise) (2023).
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