Artzi-Medvedik R, Kob R, Di Rosa M, Lattanzio F, Corsonello A, Yehoshua I, Roller-Wirnsberger RE, Wirnsberger GH, Mattace-Raso FU, Tap L, Gil PG, Formiga F, Moreno-González R, Kostka T, Guligowska A, Ärnlöv J, Carlsson AC, Freiberger E, Melzer I (2023)
Publication Type: Journal article
Publication year: 2023
Book Volume: 12
Article Number: 3959
Journal Issue: 12
DOI: 10.3390/jcm12123959
A longitudinal alteration in health-related quality of life (HRQoL) over a two-year period and its association with early-stage chronic kidney disease (CKD) progression was investigated among 1748 older adults (>75 years). HRQoL was measured by the Euro-Quality of Life Visual Analog Scale (EQ-VAS) at baseline and at one and two years after recruitment. A full comprehensive geriatric assessment was performed, including sociodemographic and clinical characteristics, the Geriatric Depression Scale-Short Form (GDS-SF), Short Physical Performance Battery (SPPB), and estimated glomerular filtration rate (eGFR). The association between EQ-VAS decline and covariates was investigated by multivariable analyses. A total of 41% of the participants showed EQ-VAS decline, and 16.3% showed kidney function decline over the two-year follow-up period. Participants with EQ-VAS decline showed an increase in GDS-SF scores and a greater decline in SPPB scores. The logistic regression analyses showed no contribution of a decrease in kidney function on EQ-VAS decline in the early stages of CKD. However, older adults with a greater GDS-SF score were more likely to present EQ-VAS decline over time, whereas an increase in the SPPB scores was associated with less EQ-VAS decline. This finding should be considered in clinical practice and when HRQoL is used to evaluate health interventions among older adults.
APA:
Artzi-Medvedik, R., Kob, R., Di Rosa, M., Lattanzio, F., Corsonello, A., Yehoshua, I.,... Melzer, I. (2023). Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study. Journal of Clinical Medicine, 12(12). https://doi.org/10.3390/jcm12123959
MLA:
Artzi-Medvedik, Rada, et al. "Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study." Journal of Clinical Medicine 12.12 (2023).
BibTeX: Download