Comparison of Dual-Source Computed Tomography for the Quantification of the Aortic Valve Area in Patients With Aortic Stenosis Versus Transthoracic Echocardiography and Invasive Hemodynamic Assessment

Ropers D, Ropers U, Marwan M, Schepis T, Pflederer T, Wechsel M, Klinghammer L, Flachskampf FA, Daniel W, Achenbach S (2009)

Publication Type: Journal article

Publication year: 2009

Journal

American Journal of Cardiology Elsevier

Book Volume: 104

Pages Range: 1561-1567

Journal Issue: 11

DOI: 10.1016/j.amjcard.2009.07.024

Abstract

We compared the measurements of the aortic valve area (AVA) using dual-source computed tomography (DSCT) in patients with mid to severe aortic stenosis to measurements using transthoracic echocardiography (TTE) and invasive hemodynamic assessment. A total of 50 patients (mean age 73 ± 10 years) with suspected aortic stenosis were included. The computed tomographic data were acquired using DSCT with standardized scan parameters (2 × 64 × 0.6 mm collimation, 330-ms rotation, 120-kV tube voltage, 560 mA/rot tube current). After injection of 35 ml contrast agent (flow rate 5 ml/s), a targeted volume data set, ranging from the top of the leaflets to the infundibulum, was acquired. Ten cross-sectional data sets (slice thickness 1 mm, no overlap, increment 0.6 mm) were reconstructed during systole in 5% increments of the R-R interval. The AVA determined in systole by planimetry was compared to the calculated AVA values using the continuity equation on TTE and the Gorlin formula on catheterization. DSCT allowed the planimetry of the AVA in all patients. The mean AVA using DSCT was 1.16 ± 0.47 cm² compared to a mean AVA of 1.04 ± 0.45 cm² using TTE and 1.06 ± 0.45 cm² using catheterization, with a significant correlation between DSCT/TTE (r = 0.93, p <0.001) and DSCT/cardiac catheterization (r = 0.97, p <0.001). However, DSCT demonstrated a slight, but significant, overestimation of the AVA compared to TTE (+0.12 ± 0.17 cm) and catheterization (+0.10 ± 0.12 cm²). In conclusion, DSCT permits one to assess the AVA with a high-image quality and diagnostic accuracy compared to TTE and invasive determination. © 2009 Elsevier Inc. All rights reserved.

Authors with CRIS profile

Dieter Ropers Medizinische Fakultät Mohamed Marwan Department of Medicine 2 – Cardiology and Angiology Lutz Klinghammer Department of Medicine 2 – Cardiology and Angiology Werner Daniel Medizinische Fakultät Stephan Achenbach Lehrstuhl für Innere Medizin II

How to cite

APA:

Ropers, D., Ropers, U., Marwan, M., Schepis, T., Pflederer, T., Wechsel, M.,... Achenbach, S. (2009). Comparison of Dual-Source Computed Tomography for the Quantification of the Aortic Valve Area in Patients With Aortic Stenosis Versus Transthoracic Echocardiography and Invasive Hemodynamic Assessment. American Journal of Cardiology, 104(11), 1561-1567. https://doi.org/10.1016/j.amjcard.2009.07.024

MLA:

Ropers, Dieter, et al. "Comparison of Dual-Source Computed Tomography for the Quantification of the Aortic Valve Area in Patients With Aortic Stenosis Versus Transthoracic Echocardiography and Invasive Hemodynamic Assessment." American Journal of Cardiology 104.11 (2009): 1561-1567.

BibTeX: Download