Regulation of bone and joint inflammation by type 2 innate lymphoid cells

Omata Y, Zaiss M, Frech M, Schett G, Tanaka S (2023)

Publication Type: Authored book

Publication year: 2023

Publisher: Elsevier

ISBN: 9780323858311

DOI: 10.1016/B978-0-323-85831-1.00026-7

Abstract

The innate and adaptive immune systems regulate inflammation in arthritis. The innate immune system works as one of the “first responders” against the invasion of pathogens, followed by adaptive immunity activation. The cross-talk between innate and adaptive immune cells has protective roles against pathogens and induces immunological responses. Recently, a new type of innate immune cells, innate lymphoid cells (ILCs), was discovered; it was found that they play a profound role in immunological responses. ILCs function closely with T helper cells, depending on their respective subsets. In this chapter, we mainly focus on one subset, type 2 ILCs (ILC2s), and review their role in inflammatory arthritis and bone homeostasis.

Authors with CRIS profile

Mario Zaiss Department of Medicine 3 – Rheumatology and Immunology Michael Frech Department of Medicine 3 – Rheumatology and Immunology Georg Schett Lehrstuhl für Innere Medizin III

How to cite

APA:

Omata, Y., Zaiss, M., Frech, M., Schett, G., & Tanaka, S. (2023). Regulation of bone and joint inflammation by type 2 innate lymphoid cells. Elsevier.

MLA:

Omata, Yasunori, et al. Regulation of bone and joint inflammation by type 2 innate lymphoid cells. Elsevier, 2023.

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