LoC-SERS toward clinical application: Quantification of antibiotics in human urine samples
Hidi IJ, Jahn M, Weber K, Pletz MW, Bocklitz TW, Cialla-May D, Popp J (2017)
Publication Type: Conference contribution
Publication year: 2017
Journal
Publisher: SPIE
Book Volume: 10080
Conference Proceedings Title: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Event location: San Francisco, CA, USA
ISBN: 9781510606012
DOI: 10.1117/12.2250533
Abstract
The determination of the concentration of xenobiotics in biological matrix followed by the change of the prescribing procedure plays a major role in the transition from general to personalized medicine. For this contribution, human urine samples collected from healthy volunteers and from patients having urinary tract infection were used as biological matrix to assess the potential and limitation of LoC-SERS to detected levofloxacin and nitroxoline. The determination of both antibiotics at clinically relevant concentrations, 1.38 mM ± 0.68 mM for levofloxacin and 10-40 μM for nitroxoline, will be presented. For quantification purposes the standard addition method is combined with LoC-SERS.
Involved external institutions
Germany (DE)How to cite
APA:
Hidi, I.J., Jahn, M., Weber, K., Pletz, M.W., Bocklitz, T.W., Cialla-May, D., & Popp, J. (2017). LoC-SERS toward clinical application: Quantification of antibiotics in human urine samples. In Tuan Vo-Dinh, Joseph R. Lakowicz (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. San Francisco, CA, USA: SPIE.
MLA:
Hidi, I. J., et al. "LoC-SERS toward clinical application: Quantification of antibiotics in human urine samples." Proceedings of the Plasmonics in Biology and Medicine XIV, San Francisco, CA, USA Ed. Tuan Vo-Dinh, Joseph R. Lakowicz, SPIE, 2017.
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