Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: From cells to clinics
Cialla-May D, Zheng XS, Weber K, Popp J (2017)
Publication Type: Journal article, Review article
Publication year: 2017
Journal
Book Volume: 46
Pages Range: 3945-3961
Journal Issue: 13
DOI: 10.1039/c7cs00172j
Abstract
The application of surface-enhanced Raman spectroscopy (SERS) in biological and biomedical detection schemes is feasible due to its excellent molecular specificity and high sensitivity as well as the capability of SERS to be performed in complex biological compositions. SERS-based investigation of cells, which are the basic structure and functional unit of organisms, represents the starting point of this review. It is demonstrated that SERS provides a deep understanding of living cells as well as their microenvironment which is needed to assess the development of diseases. The clinical relevance of SERS is proved by its application for the detection of cancer cells and tumour margins under in vivo conditions and examples for theranostic approaches are discussed. This review article provides a comprehensive overview of the recent progress within the last 3 years.
Involved external institutions
Friedrich-Schiller-Universität Jena
Germany (DE)
Leibniz-Institut für Photonische Technologien e.V.
Germany (DE)
Germany (DE)
Leibniz-Institut für Photonische Technologien e.V.
Germany (DE)
How to cite
APA:
Cialla-May, D., Zheng, X.-S., Weber, K., & Popp, J. (2017). Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: From cells to clinics. Chemical Society Reviews, 46(13), 3945-3961. https://doi.org/10.1039/c7cs00172j
MLA:
Cialla-May, Dana, et al. "Recent progress in surface-enhanced Raman spectroscopy for biological and biomedical applications: From cells to clinics." Chemical Society Reviews 46.13 (2017): 3945-3961.
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