Prolactin Receptor Isoforms as the Basis of Tissue-Specific Action of Prolactin in the Norm and Pathology
Abramicheva PA, Smirnova OV (2019)
Publication Type: Journal article, Review article
Publication year: 2019
Journal
Book Volume: 84
Pages Range: 329-345
Journal Issue: 4
DOI: 10.1134/S0006297919040011
Abstract
The review describes functional and structural features of different isoforms of prolactin receptor, mechanisms of signaling pathway activation, and molecular messengers involved in the transmission and termination of signal from the prolactin receptor isoforms. Changes in the ratio between prolactin receptor isoforms, key mediators of prolactin signal transduction and termination in various organs and tissues, are analyzed. Special attention is given to the role of molecular mediators and the ratio between the isoforms in normal physiological functions and pathologies. Approaches for therapeutic correction of prolactin signaling impairments are discussed.
Involved external institutions
Russian Federation (RU)How to cite
APA:
Abramicheva, P.A., & Smirnova, O.V. (2019). Prolactin Receptor Isoforms as the Basis of Tissue-Specific Action of Prolactin in the Norm and Pathology. Biochemistry-Moscow, 84(4), 329-345. https://dx.doi.org/10.1134/S0006297919040011
MLA:
Abramicheva, P. A., and Olga V. Smirnova. "Prolactin Receptor Isoforms as the Basis of Tissue-Specific Action of Prolactin in the Norm and Pathology." Biochemistry-Moscow 84.4 (2019): 329-345.
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