Raman spectroscopic investigation of plasma by drop coating deposition for clinical application
Huang J, Ramoji A, Kiehntopf M, Noutsias M, Guo S, Bocklitz T, Popp J, Neugebauer U (2019)
Publication Type: Conference contribution
Publication year: 2019
Publisher: OSA - The Optical Society
Book Volume: Part F142-ECBO 2019
Conference Proceedings Title: Optics InfoBase Conference Papers
Event location: Munich, NLD
ISBN: 9781557528209
DOI: 10.1117/12.2526738
Abstract
Raman spectroscopy has been applied to investigate the suitability of the drop coating deposition technique to study plasma samples from healthy donors and a patient with underlying cardiac condition. When blood plasma is deposited on a solid substrate, a droplet with coffee-ring is formed, and the plasma proteins will distribute inhomogeneously depending on the chemical and physical properties of the proteins. Changes in the fingerprint region of the Raman spectra were observed from the outer-ring and central zone of the droplet through a systematic investigation. For complete characterization of the sample, optimum measurement scheme has been proposed. To obtain clinically relevant information of the effects of immunoadsorption (IA) treatment of dilated cardiomyopathy (DCM) patient’s, Raman spectral information from outer-ring as well as from the central zone is required.
Involved external institutions
Germany (DE)How to cite
APA:
Huang, J., Ramoji, A., Kiehntopf, M., Noutsias, M., Guo, S., Bocklitz, T.,... Neugebauer, U. (2019). Raman spectroscopic investigation of plasma by drop coating deposition for clinical application. In Optics InfoBase Conference Papers. Munich, NLD: OSA - The Optical Society.
MLA:
Huang, Jing, et al. "Raman spectroscopic investigation of plasma by drop coating deposition for clinical application." Proceedings of the European Conference on Biomedical Optics, ECBO_2019, Munich, NLD OSA - The Optical Society, 2019.
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