Raman Spectroscopy to Characterize Bladder Tissue for Multidimensional Diagnostics of Cancer in Urology
Krafft C, Guo S, Bocklitz T, Popp J, Bronsert P, Miernik A (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 6
Article Number: 20203063
Journal Issue: 3
Abstract
Fiber optic Raman spectroscopy offers labelfree identification of cancer in the bladder under in vivo conditions. However, state-of-the-art Raman technology does not enable to scan the entire bladder wall. Our multidimensional approach within the project Uro-MDD combines panoramic 3D-image reconstruction of white light cystoscopy and fluorescence lifetime imaging to define regions of interest for Raman-assisted diagnostics. First Raman results are presented from human control and cancer bladder specimens that demonstrated how to obtain specific molecular information. Such Raman images can be used in a clinical setting to determine cancer margins and the resection status. Fiber probes are under development to translate the technique to in vivo screening.
Involved external institutions
Leibniz-Institut für Photonische Technologien e.V.
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
How to cite
APA:
Krafft, C., Guo, S., Bocklitz, T., Popp, J., Bronsert, P., & Miernik, A. (2020). Raman Spectroscopy to Characterize Bladder Tissue for Multidimensional Diagnostics of Cancer in Urology. Current Directions in Biomedical Engineering, 6(3). https://dx.doi.org/10.1515/cdbme-2020-3063
MLA:
Krafft, C., et al. "Raman Spectroscopy to Characterize Bladder Tissue for Multidimensional Diagnostics of Cancer in Urology." Current Directions in Biomedical Engineering 6.3 (2020).
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