Programmed cell death during retinal development of the mouse eye
Braunger BM, Demmer C, Tamm ER (2014)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2014
Journal
Publisher: Springer New York LLC
Series: Advances in Experimental Medicine and Biology
Book Volume: 801
Pages Range: 9-13
DOI: 10.1007/978-1-4614-3209-8_2
Abstract
Similar to other parts of the central nervous system, there are two types of programmed cell death during retinal development. In early development, the neuronal progenitor population is affected. In the mouse eye, this kind of programmed cell death begins at around embryonic day (E) 12.5 and peaks between E14.5 and E16.5. The second phase of programmed cell death occurs during synaptogenesis within the first 2 postnatal weeks. Important signaling mechanisms that induce programmed cell death of retinal progenitors appear to involve nerve growth factor acting on the proapoptotic receptor to p75 neurotrophin receptor (p75NTR) and transforming growth factor-β.
Involved external institutions
Germany (DE)How to cite
APA:
Braunger, B.M., Demmer, C., & Tamm, E.R. (2014). Programmed cell death during retinal development of the mouse eye. In (pp. 9-13). Springer New York LLC.
MLA:
Braunger, Barbara M., Cora Demmer, and Ernst R. Tamm. "Programmed cell death during retinal development of the mouse eye." Springer New York LLC, 2014. 9-13.
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