Cutting Edge in IFN Regulation: Inflammatory Caspases Cleave cGAS

Heidegger S, Haas T, Poeck H (2017)

Publication Type: Journal article

Publication year: 2017

Journal

Immunity Elsevier

Book Volume: 46

Pages Range: 333-335

Journal Issue: 3

DOI: 10.1016/j.immuni.2017.03.004

Abstract

Caspases have important functions beyond their established role in driving inflammation and apoptosis. In this issue of Immunity, Wang et al. (2017) demonstrate that inflammasome-triggered caspases cleave and inactivate the DNA sensor cGAS, thus restricting the type I interferon response to cytosolic DNA.

Involved external institutions

Technische Universität München (TUM) DE Germany (DE)

How to cite

APA:

Heidegger, S., Haas, T., & Poeck, H. (2017). Cutting Edge in IFN Regulation: Inflammatory Caspases Cleave cGAS. Immunity, 46(3), 333-335. https://dx.doi.org/10.1016/j.immuni.2017.03.004

MLA:

Heidegger, Simon, Tobias Haas, and Hendrik Poeck. "Cutting Edge in IFN Regulation: Inflammatory Caspases Cleave cGAS." Immunity 46.3 (2017): 333-335.

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