Exploration of artificial intelligence use with ARIES in multiple myeloma research
Loda S, Krebs J, Danhof S, Schreder M, Solimando AG, Strifler S, Rasche L, Kortuem M, Kerscher A, Knop S, Puppe F, Einsele H, Bittrich M (2019)
Publication Type: Journal article
Publication year: 2019
Journal
Book Volume: 8
Article Number: 999
Journal Issue: 7
DOI: 10.3390/jcm8070999
Abstract
Background: Natural language processing (NLP) is a powerful tool supporting the generation of Real-World Evidence (RWE). There is no NLP system that enables the extensive querying of parameters specific to multiple myeloma (MM) out of unstructured medical reports. We therefore created a MM-specific ontology to accelerate the information extraction (IE) out of unstructured text. Methods: Our MM ontology consists of extensive MM-specific and hierarchically structured attributes and values. We implemented “A Rule-based Information Extraction System” (ARIES) that uses this ontology. We evaluated ARIES on 200 randomly selected medical reports of patients diagnosed with MM. Results: Our system achieved a high F1-Score of 0.92 on the evaluation dataset with a precision of 0.87 and recall of 0.98. Conclusions: Our rule-based IE system enables the comprehensive querying of medical reports. The IE accelerates the extraction of data and enables clinicians to faster generate RWE on hematological issues. RWE helps clinicians to make decisions in an evidence-based manner. Our tool easily accelerates the integration of research evidence into everyday clinical practice.
Involved external institutions
Universitätsklinikum Würzburg
Germany (DE)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Wilhelminenspital
Austria (AT)
University of Bari Aldo Moro / Università degli Studi di Bari Aldo Moro
Italy (IT)
Germany (DE)
Julius-Maximilians-Universität Würzburg
Germany (DE)
Wilhelminenspital
Austria (AT)
University of Bari Aldo Moro / Università degli Studi di Bari Aldo Moro
Italy (IT)
How to cite
APA:
Loda, S., Krebs, J., Danhof, S., Schreder, M., Solimando, A.G., Strifler, S.,... Bittrich, M. (2019). Exploration of artificial intelligence use with ARIES in multiple myeloma research. Journal of Clinical Medicine, 8(7). https://doi.org/10.3390/jcm8070999
MLA:
Loda, Sophia, et al. "Exploration of artificial intelligence use with ARIES in multiple myeloma research." Journal of Clinical Medicine 8.7 (2019).
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