Thuering J, Rippel O, Haarburger C, Merhof D, Schad P, Bruners P, Kuhl CK, Truhn D (2020)
Publication Type: Journal article
Publication year: 2020
Book Volume: 4
Article Number: 20
Journal Issue: 1
DOI: 10.1186/s41747-020-00148-3
Background: To evaluate whether machine learning algorithms allow the prediction of Child-Pugh classification on clinical multiphase computed tomography (CT). Methods: A total of 259 patients who underwent diagnostic abdominal CT (unenhanced, contrast-enhanced arterial, and venous phases) were included in this retrospective study. Child-Pugh scores were determined based on laboratory and clinical parameters. Linear regression (LR), Random Forest (RF), and convolutional neural network (CNN) algorithms were used to predict the Child-Pugh class. Their performances were compared to the prediction of experienced radiologists (ERs). Spearman correlation coefficients and accuracy were assessed for all predictive models. Additionally, a binary classification in low disease severity (Child-Pugh class A) and advanced disease severity (Child-Pugh class ≥ B) was performed. Results: Eleven imaging features exhibited a significant correlation when adjusted for multiple comparisons with Child-Pugh class. Significant correlations between predicted and measured Child-Pugh classes were observed (ρ
APA:
Thuering, J., Rippel, O., Haarburger, C., Merhof, D., Schad, P., Bruners, P.,... Truhn, D. (2020). Multiphase CT-based prediction of Child-Pugh classification: a machine learning approach. European Radiology Experimental, 4(1). https://doi.org/10.1186/s41747-020-00148-3
MLA:
Thuering, Johannes, et al. "Multiphase CT-based prediction of Child-Pugh classification: a machine learning approach." European Radiology Experimental 4.1 (2020).
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