Autologous stem cell transplantation in multiple myeloma patients: utilization patterns and hospital effects
Jansen L, Merz M, Engelhardt M, Weisel K, Scheid C, Straka C, Langer C, Salwender H, Einsele H, Kroege N, Beelen DW, Dreger P, Goldschmidt H, Brenner H (2020)
Publication Type: Journal article
Publication year: 2020
Journal
Book Volume: 61
Pages Range: 2365-2374
Journal Issue: 10
DOI: 10.1080/10428194.2020.1768383
Abstract
Evidence on volume outcome associations for autologous stem cell transplantation (ASCT) in multiple myeloma (MM) is limited. We investigated ASCT utilization patterns and volume outcome associations in the German National Registry for Stem Cell Transplants (DRST). MM patients with an upfront ASCT between 1998 and 2014 registered in the DRST were included. ASCT utilization increased strongly from 6% to 17% between 1999 and 2013 with the largest increase for patients aged 60–64 years (8–34%). The mean number of ASCTs conducted in the hospitals per year varied (quintiles, Q1:0.0–8.2 to Q5:31.0–102.7). Center volume was not associated with survival after upfront ASCT (lowest vs. highest center volume, hazard ratios and 95% confidence intervals: 0.95 (0.76–1.18), p = 0.92). Our findings may reflect a high standard of care and degree of specialization of centers performing ASCT for MM in Germany.
Involved external institutions
Deutsches Krebsforschungszentrum (DKFZ)
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Universitätsklinikum Köln
Germany (DE)
Klinikum Kempten
Germany (DE)
Asklepios Klinik Altona
Germany (DE)
Universitätsklinikum Würzburg
Germany (DE)
Universitätsklinikum Essen
Germany (DE)
Klinikum Schwabing
Germany (DE)
Germany (DE)
Universitätsklinikum Heidelberg
Germany (DE)
Universitätsklinikum Freiburg
Germany (DE)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Germany (DE)
Universitätsklinikum Köln
Germany (DE)
Klinikum Kempten
Germany (DE)
Asklepios Klinik Altona
Germany (DE)
Universitätsklinikum Würzburg
Germany (DE)
Universitätsklinikum Essen
Germany (DE)
Klinikum Schwabing
Germany (DE)
How to cite
APA:
Jansen, L., Merz, M., Engelhardt, M., Weisel, K., Scheid, C., Straka, C.,... Brenner, H. (2020). Autologous stem cell transplantation in multiple myeloma patients: utilization patterns and hospital effects. Leukemia & Lymphoma, 61(10), 2365-2374. https://doi.org/10.1080/10428194.2020.1768383
MLA:
Jansen, Lina, et al. "Autologous stem cell transplantation in multiple myeloma patients: utilization patterns and hospital effects." Leukemia & Lymphoma 61.10 (2020): 2365-2374.
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