Tfh cells induce intratumoral tertiary lymphoid structures

Schmidleithner L, Feuerer M (2022)

Publication Type: Journal article

Publication year: 2022

Journal

Trends in Immunology Elsevier

Book Volume: 43

Pages Range: 274-276

Journal Issue: 4

DOI: 10.1016/j.it.2022.02.010

Abstract

Tertiary lymphoid structures (TLS) are highly organized ectopic structures found in nonlymphoid organs under chronic inflammatory conditions, including cancer. A recent study by Chaurio et al. reports that repression of Satb1 in CD4+ T cells can lead to increased Tfh cell differentiation, driving intratumoral TLS formation, resulting in reduced tumor growth in mice.

Involved external institutions

Leibniz-Institut für Immuntherapie (LIT) / Leibniz Institute for Immunotherapy DE Germany (DE) Universität Regensburg DE Germany (DE)

How to cite

APA:

Schmidleithner, L., & Feuerer, M. (2022). Tfh cells induce intratumoral tertiary lymphoid structures. Trends in Immunology, 43(4), 274-276. https://dx.doi.org/10.1016/j.it.2022.02.010

MLA:

Schmidleithner, Lisa, and Markus Feuerer. "Tfh cells induce intratumoral tertiary lymphoid structures." Trends in Immunology 43.4 (2022): 274-276.

BibTeX: Download