Carbon nanostructures as multi-functional drug delivery platforms

Mendes RG, Bachmatiuk A, Buechner B, Cuniberti G, Ruemmeli MH (2013)


Publication Type: Journal article

Publication year: 2013

Journal

Book Volume: 1

Pages Range: 401-428

Journal Issue: 4

DOI: 10.1039/c2tb00085g

Abstract

Nanotechnology is providing exciting and new opportunities which are likely to revolutionize future clinical practice. The use of nanoparticles for biomedical applications is particularly exciting due to their huge potential for multi-modal approaches. This includes their use as drug delivery vectors, imaging contrast agents, hyperthermia systems and molecular targeting. Their ability to cross biological barriers, for example the blood brain barrier, makes them attractive for potential treatments in neurological disorders. There is also great hope that nanostructures will serve as platforms in future cancer therapies. Current cancer fighting strategies consist primarily of surgery, radiation therapy and chemotherapy. Each of these treatments is bound by a limit, known as the therapeutic window, which, if exceeded, causes undue harm to the patient. In the ongoing quest to improve our therapeutic arsenal, nanoparticles are emerging as exciting structures for a new generation of multi-modal therapeutics. Within this context, carbon nanostructures are amongst the leading contenders as building blocks to deliver multi-function drug delivery platforms. This review examines the various properties of carbon nanostructures that allow such multi-functionality. Recent advances on the development of novel approaches for functionalization, targeting and imaging via carbon nanostructures are discussed. © 2013 The Royal Society of Chemistry.

Involved external institutions

How to cite

APA:

Mendes, R.G., Bachmatiuk, A., Buechner, B., Cuniberti, G., & Ruemmeli, M.H. (2013). Carbon nanostructures as multi-functional drug delivery platforms. Journal of Materials Chemistry B, 1(4), 401-428. https://dx.doi.org/10.1039/c2tb00085g

MLA:

Mendes, Rafael G., et al. "Carbon nanostructures as multi-functional drug delivery platforms." Journal of Materials Chemistry B 1.4 (2013): 401-428.

BibTeX: Download