Oligosaccharide-Crowned hyperbranched poly(ethyleneimine) as an additive to thin-layer chromatography systems for the separation of vitamins, amino acids and β-blocker enantiomers
Dzema D, Kartsova L, Kapizova D, Tripp S, Polikarpov N, Appelhans D, Voit B (2016)
Publication Type: Journal article
Publication year: 2016
Journal
Book Volume: 29
Pages Range: 108-112
Journal Issue: 2
Abstract
Impregnation of a stationary phase by organic and inorganic agents in high-performance thin-layer chromatography (HPTLC) may result in higher separation selectivity and resolution. This work is devoted to the application of novel core-shell polymers consisting of hyperbranched (poly(ethyleneimine)) core surrounded by oligosaccharide shell (PEI-OS) as a component of silica stationary phase in HPTLC for the separation of water-soluble vitamins, amino acids, and chiral β-blocker enantiomers. The influence of polymer structure (degree of substitution of PEI terminal amino groups with oligosaccharides and molecular weight of dendritic core [5 or 25 kDa]) as well as the content of PEI-OS in the stationary phase and a method of modification of the stationary phase on the efficiency of vitamin and amino acid determination and on the enantioselectivity factors of β-blockers separation were investigated. It was established that such polymers can be used as modifying agents of HPTLC systems for on-line preconcentration of vitamins (B2) and amino acids (lysine, tryptophan, and glutamic acids). These polymers can also be recommended as chiral selectors for the effective TLC separation of β-blockers.
Involved external institutions
Saint Petersburg State University (SPbU) / Санкт-Петербургский государственный университет (СПбГУ)
Russian Federation (RU)
Leibniz-Institut für Polymerforschung Dresden e. V.
Germany (DE)
Russian Federation (RU)
Leibniz-Institut für Polymerforschung Dresden e. V.
Germany (DE)
How to cite
APA:
Dzema, D., Kartsova, L., Kapizova, D., Tripp, S., Polikarpov, N., Appelhans, D., & Voit, B. (2016). Oligosaccharide-Crowned hyperbranched poly(ethyleneimine) as an additive to thin-layer chromatography systems for the separation of vitamins, amino acids and β-blocker enantiomers. Jpc-Journal of Planar Chromatography-Modern Tlc, 29(2), 108-112. https://dx.doi.org/10.1556/1006.2016.29.2.3
MLA:
Dzema, Daria, et al. "Oligosaccharide-Crowned hyperbranched poly(ethyleneimine) as an additive to thin-layer chromatography systems for the separation of vitamins, amino acids and β-blocker enantiomers." Jpc-Journal of Planar Chromatography-Modern Tlc 29.2 (2016): 108-112.
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