Continuous monitoring of molecular biomarkers in microfluidic devices
Idili A, Monton H, Medina-Sanchez M, Ibarlucea B, Cuniberti G, Schmidt OG, Plaxco KW, Parolo C (2022)
Publication Type: Book chapter / Article in edited volumes
Publication year: 2022
Journal
Publisher: Elsevier B.V.
Edited Volumes: Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B
Series: Progress in Molecular Biology and Translational Science
Book Volume: 187
Pages Range: 295-333
DOI: 10.1016/bs.pmbts.2021.07.027
Abstract
The ability to monitor molecular targets is crucial in fields ranging from healthcare to industrial processing to environmental protection. Devices employing biomolecules to achieve this goal are called biosensors. Over the last half century researchers have developed dozens of different biosensor approaches. In this chapter we analyze recent advances in the biosensing field aiming at adapting these to the problem of continuous molecular monitoring in complex sample streams, and how the merging of these sensors with lab-on-a-chip technologies would be beneficial to both. To do so we discuss (1) the components that comprise a biosensor, (2) the challenges associated with continuous molecular monitoring in complex sample streams, (3) how different sensing strategies deal with (or fail to deal with) these challenges, and (4) the implementation of these technologies into lab-on-a-chip architectures.
Involved external institutions
University of California
United States (USA) (US)
Leibniz-Institut für Festkörper- und Werkstoffforschung Dresden e.V. (IFW) / Leibniz Institute for Solid State and Materials Research Dresden
Germany (DE)
Technische Universität Dresden
Germany (DE)
United States (USA) (US)
Leibniz-Institut für Festkörper- und Werkstoffforschung Dresden e.V. (IFW) / Leibniz Institute for Solid State and Materials Research Dresden
Germany (DE)
Technische Universität Dresden
Germany (DE)
How to cite
APA:
Idili, A., Monton, H., Medina-Sanchez, M., Ibarlucea, B., Cuniberti, G., Schmidt, O.G.,... Parolo, C. (2022). Continuous monitoring of molecular biomarkers in microfluidic devices. In Alok Pandya, Vijai Singh (Eds.), Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B. (pp. 295-333). Elsevier B.V..
MLA:
Idili, Andrea, et al. "Continuous monitoring of molecular biomarkers in microfluidic devices." Micro/Nanofluidics and Lab-on-Chip Based Emerging Technologies for Biomedical and Translational Research Applications - Part B. Ed. Alok Pandya, Vijai Singh, Elsevier B.V., 2022. 295-333.
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