Weighted reconstruction methodology for optoacoustic tomographic imaging of heterogeneous acoustic samples

Dean-Ben XL, Ntziachristos V, Razansky D (2013)


Publication Type: Conference contribution

Publication year: 2013

Publisher: Optical Society of America

Conference Proceedings Title: Optics InfoBase Conference Papers

Event location: DEU

ISBN: 9780819496461

DOI: 10.1117/12.2033355

Abstract

Some biological samples contain strongly mismatched tissues such as bones or lungs that generally produce acoustic reflections and scattering, leading to consequent image distortion if the reconstruction is performed by assuming an acoustically homogeneous medium. A weighted optoacoustic reconstruction procedure based on statistical principles is presented herein to tomographically image tissues with strong acoustic mismatch. The procedure is based on weighting the contribution of the collected optoacoustic signals to the reconstruction with the probability that they are not affected by reflections or scattering. Since such probability depends on the available information about the distribution of optical absorbers, an iterative procedure in which the reconstructted images are used to recalculate the weighting values is presented in this work. The benefit of the reconstruction procedure described herein is showcased by reconstructing a phantom containing a straw filled with air, which mimicks air-gaps in actual biological samples. © 2013 OSA-SPIE.

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How to cite

APA:

Dean-Ben, X.L., Ntziachristos, V., & Razansky, D. (2013). Weighted reconstruction methodology for optoacoustic tomographic imaging of heterogeneous acoustic samples. In Optics InfoBase Conference Papers. DEU: Optical Society of America.

MLA:

Dean-Ben, X. Luis, Vasilis Ntziachristos, and Daniel Razansky. "Weighted reconstruction methodology for optoacoustic tomographic imaging of heterogeneous acoustic samples." Proceedings of the European Conference on Biomedical Optics, ECBO 2013, DEU Optical Society of America, 2013.

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