Induced pluripotent stem cell-derived cardiomyocytes: A versatile tool for arrhythmia research

Sinnecker D, Goedel A, Laugwitz KL, Moretti A (2013)


Publication Type: Journal article

Publication year: 2013

Journal

Book Volume: 112

Pages Range: 961-968

Journal Issue: 6

DOI: 10.1161/CIRCRESAHA.112.268623

Abstract

Induced pluripotent stem cells offer the possibility to generate patient-specific stem cell lines from individuals affected by inherited disorders. Cardiomyocytes differentiated from such patient-specific induced pluripotent stem cells lines have been used to study the pathophysiology of arrhythmogenic heart diseases, such as the long-QT syndrome or catecholaminergic polymorphic ventricular tachycardia. Testing for unwanted drug side effects or tailoring medical treatment to the specific needs of individual patients with arrhythmogenic disorders may become future applications of this emerging technology. © 2013 American Heart Association, Inc.

Involved external institutions

How to cite

APA:

Sinnecker, D., Goedel, A., Laugwitz, K.-L., & Moretti, A. (2013). Induced pluripotent stem cell-derived cardiomyocytes: A versatile tool for arrhythmia research. Circulation Research, 112(6), 961-968. https://doi.org/10.1161/CIRCRESAHA.112.268623

MLA:

Sinnecker, Daniel, et al. "Induced pluripotent stem cell-derived cardiomyocytes: A versatile tool for arrhythmia research." Circulation Research 112.6 (2013): 961-968.

BibTeX: Download